Skip to main content
Signaling pathways in mouse and human trophoblast differentiation: a comparative review
Published Web Location
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366325/pdf/nihms645576.pdfNo data is associated with this publication.
Abstract
The mouse is often used as a model for understanding human placentation and offers multiple advantages, including the ability to manipulate gene expression in specific compartments and to derive trophoblast stem cells, which can be maintained or differentiated in vitro. Nevertheless, there are numerous differences between the mouse and human placentas, only the least of which are structural. This review aims to compare mouse and human placentation, with a focus on signaling pathways involved in trophoblast lineage-specific differentiation.
Many UC-authored scholarly publications are freely available on this site because of the UC's open access policies. Let us know how this access is important for you.