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Neural stem cells sustain natural killer cells that dictate recovery from brain inflammation

Published Web Location

https://doi.org/10.1038/nn.4211
Abstract

Natural killer (NK) cells are retained and reside in the vicinity of neural stem cells (NSCs) in the brain subventricular zone during the chronic phase of multiple sclerosis in humans and its animal model in mice. In this study, the authors show that these NK cells limit NSCs' reparative capacity following brain inflammation, while NSCs promote NK survival via an interleukin-15-dependent mechanism.

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