Skip to main content
eScholarship
Open Access Publications from the University of California

Alpha-1-antitrypsin deficiency-associated panniculitis: a case report

  • Author(s): Laureano, Andre
  • Carvalho, Rodrigo
  • Chaveiro, Alexandra
  • Cardoso, Jorge
  • et al.
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International Public License
Abstract

Panniculitis is a recognized, but rare complication of α1-antitrypsin (A1AT) deficiency. Less than 60 cases have been reported, mostly in the homozygous PiZZ variant. We report the case of a 55-year old woman with A1AT panniculitis associated with the heterozygous phenotype PiMS and discrete reduction of A1AT serum levels. In addition, the pathophysiology of the disease, clinical and histopathological features, and current treatment possibilities are briefly reviewed.

Main Content
Current View