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Open Access Publications from the University of California

Pink verrucous plaque in a man with systemic mastocytosis

  • Author(s): Terrell, Jessica R
  • Urban, Jennifer R
  • Fung, Maxwell A
  • Tartar, Danielle M
  • Kiuru, Maija
  • et al.
Creative Commons 'BY-NC-ND' version 4.0 license

Porokeratosis ptychotropica is a rare and commonly misdiagnosed subtype of porokeratosis involving the body folds. We present a 53-year-old man with systemic mastocytosis who presented with a pruritic, verrucous plaque in the gluteal fold that showed multiple cornoid lamellae on histopathologic evaluation, diagnostic of porokeratosis ptychotropica. Various treatments have been reported, including topical corticosteroids, retinoids, vitamin D analogs, calcineurin inhibitors, imiquimod, phototherapy, cryotherapy, or ablative laser therapy, but recurrences are common.

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