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Making C–N Bonds – From Fundamental Catalysis to 3D Spatial Omics

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My graduate studies in Professor Vy M. Dong’s lab at the University of California, Irvine, have focused on the development of new reaction methodology, with a strong focus toward C–N bond formation. This includes the development of an atom economic hydroamination using feedstock dienes and pyrazoles, the efficient macrocyclization of peptidyl natural products using dehydroamino acids as traceless turn inducers, the design and synthesis of novel photocleavable cross linkers, and the introduction of unique azatricyclic scaffolds as potential benzene mimetics. Through these efforts, we aim to further contribute to the field of organic synthesis, developing robust, cost effective transformations that access synthetically complex building blocks in high efficiency and selectivity.

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This item is under embargo until April 17, 2025.