MsFLASH participants' priorities for alleviating menopausal symptoms
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MsFLASH participants' priorities for alleviating menopausal symptoms

  • Author(s): Carpenter, Janet S
  • Woods, Nancy F
  • Otte, Julie L
  • Guthrie, Katherine A
  • Hohensee, Chancellor
  • Newton, Katherine M
  • Joffe, Hadine
  • Cohen, Lee
  • Sternfeld, Barbara
  • Lau, R Jane
  • Reed, Susan D
  • La Croix, Andrea Z
  • et al.

Published Web Location

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4732703/
No data is associated with this publication.
Abstract

Objective To describe self-reported menopausal symptom priorities and their association with demographics and other symptoms among participants in an intervention trial for vasomotor symptoms (VMS). Methods Cross-sectional study embedded in the MsFLASH 02 trial, a three by two factorial design of yoga vs. exercise vs. usual activity and omega-3-fatty acid vs. placebo. At baseline, women (n=354) completed hot flash diaries, a card sort task to prioritize symptoms they would most like to alleviate, and standardized questionnaires. Results The most common symptom priorities were: VMS (n=322), sleep (n=191), concentration (n=140), and fatigue (n=116). In multivariate models, (1) women who chose VMS as their top priority symptom (n=210) reported significantly greater VMS severity (p=0.004) and never smoking (p=0.012) and (2) women who chose sleep as their top priority symptom (n=100), were more educated (p≤0.001) and had worse sleep quality (p<0.001). ROC curves identified sleep scale scores that were highly predictive of ranking sleep as a top priority symptom. Conclusions Among women entering an intervention trial for VMS and with relatively low prevalence of depression and anxiety, VMS was the priority symptom for treatment. A card sort may be a valid tool for quickly assessing symptom priorities in clinical practice and research.

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