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Open Access Publications from the University of California

Pathogen and antimicrobial resistance surveillance in Ugandan HIV positive adults with pneumonia

Abstract

• Lower respiratory tract infections are the top cause of infectious disease-related deaths in the world.

• The causative pathogen is detectable in only 38% of adults with community acquired pneumonia.

• Time to diagnosis of pathogen is directly correctly with mortality.

• The widespread use of broad-spectrum empiric treatment contributes to the proliferation of antimicrobial resistance.

• Next Generation Sequencing could offer potential for early identification.