A consensus definition for lamellar macular hole
Skip to main content
Open Access Publications from the University of California


UCLA Previously Published Works bannerUCLA

A consensus definition for lamellar macular hole

  • Author(s): Hubschman, Jean-Pierre;
  • Govetto, Andrea;
  • Spaide, Richard;
  • Schumann, RG;
  • Steel, David H;
  • Figueroa, Marta;
  • Sebag, J;
  • Gaudric, Alain;
  • Staurenghi, Giovanni;
  • Haritoglou, Christos;
  • Kazuaki, Kadonosono;
  • Thompson, John;
  • Chang, Stanley;
  • Bottoni, Ferdinando;
  • Tadayoni, Ramin
  • et al.

Background: A consensus on an optical coherence tomography (OCT) definition of lamellar macular hole (LMH) and similar conditions is needed. Methods: The panel reviewed relevant peer-reviewed literature to reach a consensus on LMH definition and to differentiate LMH from other similar conditions. Results: The panel reached a consensus on the definition of 3 clinical entities: LMH, epiretinal membrane (ERM) foveoschisis and macular pseudohole (MPH). LMH definition is based on 3 mandatory criteria and 3 optional anatomical features. The 3 mandatory criteria are the presence of irregular foveal contour, the presence of a foveal cavity with undermined edges, and the apparent loss of foveal tissue. Optional anatomical features include the presence of epiretinal proliferation, the presence of a foveal bump and the disruption of the ellipsoid line. ERM foveoschisis definition is based on 2 mandatory criteria: the presence of ERM and the presence of schisis at the level of Henle’s fiber layer. Three optional anatomical features can also be present: the presence of microcystoid spaces in the inner nuclear layer (INL), an increase of retinal thickness, and the presence of retinal wrinkling. MPH definition is based on 3 mandatory criteria and 2 optional anatomical features. Mandatory criteria include the presence of a foveal sparing ERM, the presence of a steepened foveal profile and an increased central retinal thickness. Optional anatomical features are the presence of microcystoid spaces in the INL and a normal retinal thickness. Conclusions: The use of the proposed definitions may provide uniform language for clinicians and future research.

Many UC-authored scholarly publications are freely available on this site because of the UC's open access policies. Let us know how this access is important for you.

Main Content
For improved accessibility of PDF content, download the file to your device.
Current View