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Open Access Publications from the University of California

Paraneoplastic erythema annulare centrifugum eruption (PEACE)

  • Author(s): Mu, Euphemia W
  • Sanchez, Miguel
  • Mir, Adnan
  • Meehan, Shane A
  • Pomeranz, Miriam Keltz
  • et al.
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International Public License

Erythema annulare centrifugum (EAC) is a reactive erythema with distinct, annular, erythematous plaques with trailing scale. This condition has been associated with various etiologies, which include an associated malignant condition. EAC with cancers or paraneoplastic erythema annulare centrifugum eruptions (PEACE), is more likely to be associated with lymphoproliferative malignancies such as lymphomas and leukemias. Histopathologic features include a superficial and deep, lymphohistiocytic perivascular infiltrate. We present a patient with a history of diffuse large B cell lymphoma in remission for two years, who presented with a one-year history of EAC.

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