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Understanding the Pathogenesis of Streptococcus iniae Infection in Fish and Development of an Effective Vaccine for Use in Aquaculture

  • Author(s): Nizet, Victor
  • et al.
Abstract

S. iniae infection has emerged as a serious fish health and economic problem in intensive U.S. aquaculture operations. Current antibiotic options are few and possess severe practical limitations and potential adverse environmental impacts. We believe the major factor contributing to the large burden of S. iniae disease in aquaculture is the lack of fundamental knowledge of S. iniae virulence factors and the fundamental pathogenesis of infection.

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