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Dermatomyositis, clinically presenting with cutaneous ulcers, with histopathologic evidence of perforating collagenosis
- Rosenstein, Rachel;
- Martires, Kathryn;
- Christman, Mitalee;
- Terushkin, Vitaly;
- Meehan, Shane A;
- Seminara, Nicole;
- Golden, Brian D;
- Franks, Jr, Andrew G
- et al.
Abstract
Dermatomyositis is a systemic, autoimmune diseasewith a variety of clinical features that often includemyositis and characteristic cutaneous findings. Asubset of patients with dermatomyositis developcutaneous ulcers, often in the setting of vasculitis orvasculopathy. We present a case of dermatomyositiswith cutaneous ulcers that show perforatingcollagenosis on histopathologic examination.Acquired reactive perforating collagenosistypically occurs in the setting of diabetes mellitus,chronic renal failure, and other pruritic conditions,and this case represents a rare association withdermatomyositis, which may ultimately be helpful inelucidating the pathophysiology of this perforatingdisorder.
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