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Open Access Publications from the University of California

Dermatomyositis, clinically presenting with cutaneous ulcers, with histopathologic evidence of perforating collagenosis

  • Author(s): Rosenstein, Rachel
  • Martires, Kathryn
  • Christman, Mitalee
  • Terushkin, Vitaly
  • Meehan, Shane A
  • Seminara, Nicole
  • Golden, Brian D
  • Franks, Jr, Andrew G
  • et al.
Creative Commons 'BY-NC-ND' version 4.0 license

Dermatomyositis is a systemic, autoimmune diseasewith a variety of clinical features that often includemyositis and characteristic cutaneous findings. Asubset of patients with dermatomyositis developcutaneous ulcers, often in the setting of vasculitis orvasculopathy. We present a case of dermatomyositiswith cutaneous ulcers that show perforatingcollagenosis on histopathologic examination.Acquired reactive perforating collagenosistypically occurs in the setting of diabetes mellitus,chronic renal failure, and other pruritic conditions,and this case represents a rare association withdermatomyositis, which may ultimately be helpful inelucidating the pathophysiology of this perforatingdisorder.

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