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Development: Scaling to Size by Protease Inhibition
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https://doi.org/10.1016/j.cub.2013.06.055Abstract
The dorsal half of bisected Xenopus laevis embryos can regenerate a well-proportioned organism on a smaller scale. A new study indicates that the removal of ventral tissue generates a steeper Chordin gradient by reducing Sizzled, a secreted inhibitor of Tolloid chordinases.
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