Medical Student Research Forum Posters

• Isotretinoin (13-cis-retinoic acid) is a retinoid or vitamin A derivative widely used to treat severe acne vulgaris.

• Decreases sebum production and prevents comedo formation.

• Isotretinoin use is associated with a variety of toxicities: developmental, cutaneous, musculoskeletal, etc.

• including hyperosteosis and premature epiphyseal closure at high doses. 

• No studies examining pediatric growth in patients treated with isotretinoin at doses appropriate for severe, recalcitrant acne vulgaris treatment.