Erythrodermic Darier disease associated with metastatic lung adenocarcinoma
- Author(s): Hendricks, Aleksi J
- Maarouf, Melody
- Mills, Brandy W
- Bertoch, Spencer T
- Davis, Tracy L
- Shi, Vivian Y
- et al.
Published Web Locationhttps://doi.org/10.5070/D3267049555
We present a patient with erythrodermic Darier disease occurring in temporal association with diagnosis of metastatic lung adenocarcinoma. The patient presented with eroded and crusted keratotic papules and plaques over greater than 90% body surface area with extensive secondary impetiginization. Given a longstanding history of pruritic eruption, this presentation represents a paraneoplastic flare of an underlying genodermatosis. Near total resolution was achieved with chemotherapy and topical corticosteroids.