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Pathways to zoonotic spillover
- Plowright, Raina K;
- Parrish, Colin R;
- McCallum, Hamish;
- Hudson, Peter J;
- Ko, Albert I;
- Graham, Andrea L;
- Lloyd-Smith, James O
Published Web Location
https://doi.org/10.1038/nrmicro.2017.45Abstract
Zoonotic diseases present a substantial global health burden. In this Opinion article, Plowrightet al. present an integrative conceptual and quantitative model that reveals that all zoonotic pathogens must overcome a hierarchical series of barriers to cause spillover infections in humans.
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