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Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer
- Amundadottir, Laufey;
- Kraft, Peter;
- Stolzenberg-Solomon, Rachael Z;
- Fuchs, Charles S;
- Petersen, Gloria M;
- Arslan, Alan A;
- Bueno-de-Mesquita, H Bas;
- Gross, Myron;
- Helzlsouer, Kathy;
- Jacobs, Eric J;
- LaCroix, Andrea;
- Zheng, Wei;
- Albanes, Demetrius;
- Bamlet, William;
- Berg, Christine D;
- Berrino, Franco;
- Bingham, Sheila;
- Buring, Julie E;
- Bracci, Paige M;
- Canzian, Federico;
- Clavel-Chapelon, Françoise;
- Clipp, Sandra;
- Cotterchio, Michelle;
- de Andrade, Mariza;
- Duell, Eric J;
- Fox Jr, John W;
- Gallinger, Steven;
- Gaziano, J Michael;
- Giovannucci, Edward L;
- Goggins, Michael;
- González, Carlos A;
- Hallmans, Göran;
- Hankinson, Susan E;
- Hassan, Manal;
- Holly, Elizabeth A;
- Hunter, David J;
- Hutchinson, Amy;
- Jackson, Rebecca;
- Jacobs, Kevin B;
- Jenab, Mazda;
- Kaaks, Rudolf;
- Klein, Alison P;
- Kooperberg, Charles;
- Kurtz, Robert C;
- Li, Donghui;
- Lynch, Shannon M;
- Mandelson, Margaret;
- McWilliams, Robert R;
- Mendelsohn, Julie B;
- Michaud, Dominique S;
- Olson, Sara H;
- Overvad, Kim;
- Patel, Alpa V;
- Peeters, Petra HM;
- Rajkovic, Aleksandar;
- Riboli, Elio;
- Risch, Harvey A;
- Shu, Xiao-Ou;
- Thomas, Gilles;
- Tobias, Geoffrey S;
- Trichopoulos, Dimitrios;
- Van Den Eeden, Stephen K;
- Virtamo, Jarmo;
- Wactawski-Wende, Jean;
- Wolpin, Brian M;
- Yu, Herbert;
- Yu, Kai;
- Zeleniuch-Jacquotte, Anne;
- Chanock, Stephen J;
- Hartge, Patricia;
- Hoover, Robert N
Abstract
Stephen Chanock and colleagues report a genome-wide association study of pancreatic cancer. They identify common variants at the ABO blood group locus associated with susceptibility to pancreatic cancer, consistent with previous epidemiological evidence suggesting that individuals with A or B blood types have greater risk of this cancer than individuals with blood type O.
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