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Nanofilaments on glioblastoma exosomes revealed by peak force microscopy

Published Web Location

https://doi.org/10.1098/rsif.2013.1150
Abstract

Exosomes are sub-100 nm extracellular vesicles secreted by normal and cancer cells. We present a high-resolution structure of previously unidentified nanofilaments on glioblastoma-derived exosomes, using nanoscale peak force imaging. These stiff, adhesive, trypsin- and RNAse-resistant surface nanofilaments add a new dimension to the current structural knowledge of exosome-mediated intercellular communication.

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