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Open Access Publications from the University of California

Primary cutaneous marginal-zone lymphoma

  • Author(s): Farhadian, Joshua
  • Terushkin, Vtaly
  • Meehan, Shane A
  • Latkowski, Jo-Ann
  • et al.
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International Public License

Primary cutaneous B cell lymphomas (PCBCL) are thesecond most common type of primary cutaneouslymphoma. The three main types of PCBCL areprimary cutaneous marginal-zone lymphoma(PCMZL), primary cutaneous follicle-centerlymphoma, and primary cutaneous diffuse largeB-cell lymphoma, leg type. PCMZL has an indolentcourse with a five-year survival rate approaching99%. Lesions most often present on the trunk or armas erythematous-to-violaceous papules, plaques, ornodules. Approximately one-half of patients havesolitary skin lesions. Treatment options includesurgery, radiation, and topical, intralesional orsystemic therapy. We present the case of a 33-yearoldHispanic woman with firm, pruritic, pink papuleson the forehead and cheeks, who was diagnosedwith PCMZL.

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