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Open Access Publications from the University of California

Annular elastolytic giant cell granuloma: a “visible” diagnosis

  • Author(s): Raposo, Inês
  • Mota, Fernando
  • Lobo, Inês
  • Brandão, José Ricardo
  • Selores, Manuela
  • et al.
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International Public License

Annular elastolytic giant cell granuloma (AEGCG) is a rare granulomatous skin disease of undetermined cause, characterized by annular plaques with raised erythematous borders in sun-exposed skin. The typical histologic features are dermal infiltration by multinucleated giant cells, elastin degeneration, and elastophagocytosis. The authors describe a clinical case of AEGCG, which exhibited an excellent response to hydroxycloroquine.

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