Department of Pharmaceutical Sciences, UCI

eScholarship stats: Breakdown by Item for May through August, 2026

Item	Title	Total requests	Download	View-only	%Dnld
42v877kg	Purified and specific cytoplasmic pollen extract: a non-hormonal alternative for the treatment of menopausal symptoms.	906	50	856	5.5%
5754g6w5	CGRP as the target of new migraine therapies — successful translation from bench to clinic	889	379	510	42.6%
3t1422jb	Hormonal and Inflammatory Responses to Different Types of Sprint Interval Training	737	76	661	10.3%
6sd403pz	Experimental and Calculated Small Molecule Hydration Free Energies	711	0	711	0.0%
5zn9j1x1	Unique, long-term effects of nicotine on adolescent brain	654	102	552	15.6%
2bb550m5	Protein Folding Using a Vortex Fluidic Device	649	492	157	75.8%
75g75986	Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)	646	457	189	70.7%
2hb925zp	The XNA alphabet	644	272	372	42.2%
426788xv	Exercise activates the endocannabinoid system	574	116	458	20.2%
0xb566s2	Heart Rate Recovery from 1 Minute of Exercise in Children and Adults	542	345	197	63.7%
80s4q8pv	2023 updated MASCC/ESMO consensus recommendations: prevention of nausea and vomiting following high-emetic-risk antineoplastic agents	495	189	306	38.2%
8x57w6r7	The quality and safety of Rhodiola rosea supplements on the U.S. market: An analysis of biomarkers, heavy metals, and pesticide residues.	492	125	367	25.4%
5nm360td	HDV family of self-cleaving ribozymes.	484	314	170	64.9%
9wk3d379	Guidelines for the use and interpretation of assays for monitoring autophagy	484	251	233	51.9%
8x86w742	The Effect of a Brief Sprint Interval Exercise on Growth Factors and Inflammatory Mediators	465	108	357	23.2%
1q390115	Mechanically activated ion channel Piezo1 modulates macrophage polarization and stiffness sensing	441	233	208	52.8%
73t3849h	Definitions and Guidelines for Assessment of Wounds and Evaluation of Healing	434	139	295	32.0%
9rj0k7s3	Religious Perspectives on Embryonic Stem Cell Research	430	87	343	20.2%
5061663w	Accurate and Reliable Prediction of Relative Ligand Binding Potency in Prospective Drug Discovery by Way of a Modern Free-Energy Calculation Protocol and Force Field	429	338	91	78.8%
0474s9f4	Minimal clinically important difference of the EORTC QLQ-CIPN20 for worsening peripheral neuropathy in patients receiving neurotoxic chemotherapy	425	138	287	32.5%
1qh5k290	Trick or treat from food endocannabinoids?	423	123	300	29.1%
2673r0ws	Goods and Bads of the Endocannabinoid System as a Therapeutic Target: Lessons Learned after 30 Years	423	259	164	61.2%
5pq2n1zr	Bioorthogonal chemistry	419	149	270	35.6%
9z7112ns	Potassium leak channels and the KCNK family of two-p-domain subunits	415	63	352	15.2%
21f0c76m	The molecular logic of endocannabinoid signalling	414	91	323	22.0%
2j06b86g	Multimodal diagnosis of cerebrospinal fluid rhinorrhea: State of the art review and emerging concepts	397	246	151	62.0%
20c4h68b	Temporal dynamics of the multi-omic response to endurance exercise training	396	205	191	51.8%
753782f6	Efficacy of Alternate-Day Dosing Versus Daily Dosing of Atorvastatin	395	182	213	46.1%
9nf911g2	The Nuclear Receptor Peroxisome Proliferator-Activated Receptor-α Mediates the Anti-Inflammatory Actions of Palmitoylethanolamide	390	52	338	13.3%
9jh0n1xr	A survey of best practices for RNA-seq data analysis	389	49	340	12.6%
5w93d8tm	A study in Renaissance psychotropic plant ointments.	372	292	80	78.5%
4kh3t8d3	Shorter Is Better: The α‑(l)‑Threofuranosyl Nucleic Acid Modification Improves Stability, Potency, Safety, and Ago2 Binding and Mitigates Off-Target Effects of Small Interfering RNAs	370	286	84	77.3%
3kb6r967	Heterogeneous Skeletal Muscle Cell and Nucleus Populations Identified by Single-Cell and Single-Nucleus Resolution Transcriptome Assays.	363	127	236	35.0%
5h41q26c	Plaque-associated human microglia accumulate lipid droplets in a chimeric model of Alzheimer’s disease	360	30	330	8.3%
4d39h2wz	Distinct but Concerted Roles of ATR, DNA-PK, and Chk1 in Countering Replication Stress during S Phase	348	28	320	8.0%
26w0671j	Sexual dimorphism shapes renal metabolic adaptation to a ketogenic diet	347	257	90	74.1%
1hg0j39v	Adolescent exposure to low-dose THC disrupts energy balance and adipose organ homeostasis in adulthood	339	230	109	67.8%
1gk8m36j	Tuning immunity through tissue mechanotransduction	334	162	172	48.5%
040636gp	Truncated pyridinylbenzylamines: Potent, selective, and highly membrane permeable inhibitors of human neuronal nitric oxide synthase	327	301	26	92.0%
6bs3v89c	Overview of Drug-Drug Interactions Between Ritonavir-Boosted Nirmatrelvir (Paxlovid) and Targeted Therapy and Supportive Care for Lung Cancer	324	122	202	37.7%
7jc0z77p	The Open Force Field Initiative: Open Software and Open Science for Molecular Modeling	322	149	173	46.3%
49d1030j	How custom polymerases are driving innovation in synthetic biology	320	249	71	77.8%
5692k3zv	The Brain’s Reward System in Health and Disease	315	161	154	51.1%
1f49t00m	Cardiovascular adverse reactions associated with Guarana: is there a causal effect?	314	59	255	18.8%
6451g36j	Adverse Effects of Amiodarone	311	173	138	55.6%
4084b95n	Structures of Cytochrome P450 Enzymes	309	227	82	73.5%
8c65j530	Concentrations of Tire Additive Chemicals and Tire Road Wear Particles in an Australian Urban Tributary	308	206	102	66.9%
4tv6j3qd	Predicting Binding Free Energies	302	47	255	15.6%
6zj434ss	PER2 Controls Lipid Metabolism by Direct Regulation of PPARγ	300	84	216	28.0%
6zz4w6mf	Two-Pore Domain Potassium Channels	297	198	99	66.7%

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