- Chen, Aaron;
- Lieu, Deborah K;
- Freschauf, Lauren;
- Lew, Valerie;
- Sharma, Himanshu;
- Wang, Jiaxian;
- Nguyen, Diep;
- Karakikes, Ioannis;
- Hajjar, Roger J;
- Gopinathan, Ajay;
- Botvinick, Elliot;
- Fowlkes, Charless C;
- Li, Ronald A;
- Khine, Michelle
A biomimetic substrate for cell-culture is fabricated by plasma treatment of a prestressed thermoplastic shrink film to create tunable multiscaled alignment "wrinkles". Using this substrate, the functional alignment of human embryonic stem cell derived cardiomyocytes is demonstrated.