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Scholarly Works (2 results)

Article
Peer Reviewed

PTPN22 Association in Systemic Lupus Erythematosus (SLE) with Respect to Individual Ancestry and Clinical Sub-Phenotypes

Criswell, Lindsey;
Chung, Sharon;
Namjou, B;
Kim-Howard, X;
Sun, C;
Adler, A;
Chung, SA;
Kaufman, KM;
Kelly, JA;
Glenn, SB;
Guthridge, JM;
Scofield, RH

UC San Francisco Previously Published Works (2013)

Protein tyrosine phosphatase non-receptor type 22 (PTPN22) is a negative regulator of T-cell activation associated with several autoimmune diseases, including systemic lupus erythematosus (SLE). Missense rs2476601 is associated with SLE in individuals with

Article
Peer Reviewed

Admixture Mapping in Lupus Identifies Multiple Functional Variants within IFIH1 Associated with Apoptosis, Inflammation, and Autoantibody Production

Criswell, Lindsey;
Molineros, JE;
Maiti, AK;
Sun, C;
Looger, LL;
Han, S;
Kim-Howard, X;
Glenn, S;
Adler, A;
Kelly, JA;
Niewold, TB

UC San Francisco Previously Published Works (2013)

Systemic lupus erythematosus (SLE) is an inflammatory autoimmune disease with a strong genetic component. African-Americans (AA) are at increased risk of SLE, but the genetic basis of this risk is largely unknown. To identify causal variants in SLE loci in