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Open Access Publications from the University of California

Scholarly Works (3 results)

  • Article
  • Peer Reviewed
Dermatology Online Journal, Volume 21, Issue 7 (2015)

Background: Patients with psoriasis are often dissatisfied with available treatments, but contributing factors are not well defined.

Objective: Examine relationships between psoriasis severity, patient characteristics, and treatment satisfaction.

Methods: Patients with psoriasis were classified into mild and moderate-to-severe groups based on self-reported data. Demographics, comorbidities, symptoms, and multiple treatment satisfaction outcomes were compared between groups. Predictors of patient satisfaction with treatment were examined using linear regression models.

Results: The analyses included 773 patients (407 mild; 366 moderate-to-severe). The percentage of patients reporting satisfaction with treatment was low overall, ranging from 8.6% to 61.7% for the mild and 13.9% to 49.5% for the moderate-to-severe group. Satisfaction among biologics users was also low (≤53%; 50% of satisfaction rates <40%). Regression results consistently showed greater dissatisfaction with current treatment among moderately to severely affected patients.

Conclusion: Many psoriasis patients were dissatisfied with their treatment; moderate-to-severe patients expressed significantly less satisfaction than mild patients.

    Cover page: Psoriasis disease severity affects patient satisfaction with treatmentCreative Commons 'BY-NC-ND' version 4.0 license
    • Article
    • Peer Reviewed
    UC San Francisco Previously Published Works (2018)
    The 5th Scientific Conference of the International Pemphigus and Pemphigoid Foundation (IPPF), "Pemphigus and Pemphigoid: A New Era of Clinical and Translational Science" was held in Orlando, Florida, on May 15-16, 2018. Scientific sessions covered recent, ongoing, and future clinical trials in pemphigus and bullous pemphigoid, disease activity and quality of life instruments, and the IPPF Natural History Study. Furthermore, the meeting provided an opportunity to hear firsthand from patients, investigators, and industry about their experience enrolling for clinical trials.
      Cover page: Perspective From the 5th International Pemphigus and Pemphigoid Foundation Scientific Conference
      • Article
      • Peer Reviewed
      UC Irvine Previously Published Works (2020)

      Background

      Several European countries recently developed international diagnostic and management guidelines for pemphigus, which have been instrumental in the standardization of pemphigus management.

      Objective

      We now present results from a subsequent Delphi consensus to broaden the generalizability of the recommendations.

      Methods

      A preliminary survey, based on the European Dermatology Forum and the European Academy of Dermatology and Venereology guidelines, was sent to a panel of international experts to determine the level of consensus. The results were discussed at the International Bullous Diseases Consensus Group in March 2016 during the annual American Academy of Dermatology conference. Following the meeting, a second survey was sent to more experts to achieve greater international consensus.

      Results

      The 39 experts participated in the first round of the Delphi survey, and 54 experts from 21 countries completed the second round. The number of statements in the survey was reduced from 175 topics in Delphi I to 24 topics in Delphi II on the basis of Delphi results and meeting discussion.

      Limitations

      Each recommendation represents the majority opinion and therefore may not reflect all possible treatment options available.

      Conclusions

      We present here the recommendations resulting from this Delphi process. This international consensus includes intravenous CD20 inhibitors as a first-line therapy option for moderate-to-severe pemphigus.
        Cover page: Diagnosis and management of pemphigus: Recommendations of an international panel of experts
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