Search

Scholarly Works (1 results)

Article
Peer Reviewed

Single-cell DNA sequencing reveals complex mechanisms of resistance to quizartinib

Peretz, Cheryl AC;
McGary, Lisa HF;
Kumar, Tanya;
Jackson, Hunter;
Jacob, Jose;
Durruthy-Durruthy, Robert;
Levis, Mark J;
Perl, Alexander;
Huang, Benjamin J;
Smith, Catherine C

UC San Francisco Previously Published Works (2021)

Single-cell sequencing exposes previously unmeasurable complexity of tumor heterogeneity and clonal evolution on quizartinib. Single-cell sequencing reveals on- and off-target mechanisms of resistance to quizartinib, which can preexist therapy.

Cover page: Single-cell DNA sequencing reveals complex mechanisms of resistance to quizartinib