- Gestwicki, Jason;
- Wang, AM;
- Miyata, Y;
- Klinedinst, S;
- Peng, HM;
- Chua, JP;
- Komiyama, T;
- Li, X;
- Morishima, Y;
- Merry, DE;
- Pratt, WB
We sought new strategies to reduce amounts of the polyglutamine androgen receptor (polyQ AR) and achieve benefits in models of spinobulbar muscular atrophy, a protein aggregation neurodegenerative disorder. Proteostasis of the polyQ AR is controlled by the