- Degrado, William;
- Balgi, AD;
- Wang, J;
- Cheng, DYH;
- Ma, C;
- Pfeifer, TA;
- Shimizu, Y;
- Anderson, HJ;
- Pinto, LH;
- Lamb, RA;
- DeGrado, WF
The M2 proton channel of the influenza A virus is the target of the anti-influenza drugs amantadine and rimantadine. The effectiveness of these drugs has been dramatically limited by the rapid spread of drug resistant mutations, mainly at sites S31N, V27A
