- Coughlin, Shaun;
- Zhang, C;
- Srinivasan, Y;
- Arlow, DH;
- Fung, JJ;
- Palmer, D;
- Zheng, Y;
- Green, HF;
- Pandey, A;
- Dror, RO;
- Shaw, DE
Protease-activated receptor 1 (PAR1) is the prototypical member of a family of G-protein-coupled receptors that mediate cellular responses to thrombin and related proteases. Thrombin irreversibly activates PAR1 by cleaving the amino-terminal exodomain of t
