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Scholarly Works (2 results)

Article
Peer Reviewed

Gli as a Novel Therapeutic Target in Malignant Pleural Mesothelioma

Jablons, David;
Li, H;
Lui, N;
Cheng, T;
Tseng, HHK;
Yue, D;
Giroux-Leprieur, E;
Do, HT;
Sheng, Q;
Jin, JQ;
Luh, TW

UC San Francisco Previously Published Works (2013)

Malignant pleural mesothelioma (MPM) is a highly aggressive tumor with poor prognosis. Current treatment is rarely curative, thus novel meaningful therapies are urgently needed. Inhibition of Hedgehog (Hh) signaling at the cell membrane level in several ca

Article
Peer Reviewed

Hedgehog/Gli promotes epithelial-mesenchymal transition in lung squamous cell carcinomas

Jablons, David;
Yue, D;
Li, H;
Che, J;
Zhang, Y;
Tseng, HHK;
Jin, JQ;
Luh, TM;
Giroux-Leprieur, E;
Mo, M;
Zheng, Q

UC San Francisco Previously Published Works (2014)

Background: Squamous cell carcinomas (SCC) account for approximately 30% of non-small cell lung cancer. Investigation of the mechanism of invasion and metastasis of lung SCC will be of great help for the development of meaningful targeted therapeutics. Thi