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Open Access Publications from the University of California

Gli as a Novel Therapeutic Target in Malignant Pleural Mesothelioma

  • Author(s): Jablons, David
  • Li, H
  • Lui, N
  • Cheng, T
  • Tseng, HHK
  • Yue, D
  • Giroux-Leprieur, E
  • Do, HT
  • Sheng, Q
  • Jin, JQ
  • Luh, TW
  • et al.

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Malignant pleural mesothelioma (MPM) is a highly aggressive tumor with poor prognosis. Current treatment is rarely curative, thus novel meaningful therapies are urgently needed. Inhibition of Hedgehog (Hh) signaling at the cell membrane level in several ca

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