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Scholarly Works (4 results)

  • Thesis
  • Peer Reviewed
UC San Diego Electronic Theses and Dissertations (2021)

This dissertation views art education and exhibitions as important actors in state- and nation-building in the Republic of China (1912-1949). State-building constructed institutional infrastructure to bind and govern, and nation-building institutionalized cultural history to formulate the imagined community. Both state- and nation-building were institution-building. Gradually, the managerial leadership of Republican China became a meta-institution that further institutionalized other institutions into a system. This system assumed intellectual leadership, defined and evaluated art, distinguished art from non-art, and presented art to the artworld public. Through collective art activities and shared art conventions, the individual art institution and network of art institutions functioned as socializing structures that reproduced cultural powers reversely enhancing the socio-political institutions. Inspired by Cai Yuanpei’s slogan “aesthetic education as a substitute for religion,” the four-chapter dissertation goes from the iconoclasm of the heavenly mandate, to the voice for one’s own art history, then to the mass art that coalesced professional education and economic activities, and finally to the political officialization of national arts – a new form of enchantment in a modern nation-state.

The first chapter digs into the rapidly changing social and institutional properties of the in situ Institute for Displaying Antiquities (1914-1948). The public accessibility to the Forbidden City and emptied throne desacralized the cosmic and political symbols. The second chapter looks at the two state-subsidized art activities overseas. The two exhibitions spoke for the concept and history of Chinese art in Europe from the Chinese perspectives. The third chapter explores the interdependence between production, commerce, art, national salvation, nationalism and urban modernity. The chapter investigates the national products and the consumer identity, and examines how a spectator-market could redefine the masses’ spatiotemporal understanding of the nation and the presence. Last but not least, the fourth chapter on the Second National Arts Exhibition (1937) discusses how the eclectic assembly of arts and crafts presenting the past, the present, the future, the indigenous, and the foreign could together construct the presence of the imagined community in the geopolitical boundary.

    Cover page: Displacement and Anachronism: Art Education and Exhibitions in Meta-Institutionalizing China, 1912-1937
    • Article
    • Peer Reviewed
    UC Irvine Previously Published Works (2016)

    Unlabelled

    Individuals with chronic stroke have limited options for hand rehabilitation at home. Here, we sought to determine the feasibility and efficacy of home-based MusicGlove therapy. Seventeen participants with moderate hand impairment in the chronic phase of stroke were randomized to 3 wk of home-based exercise with either the MusicGlove or conventional tabletop exercises. The primary outcome measure was the change in the Box and Blocks test score from baseline to 1 mo posttreatment. Both groups significantly improved their Box and Blocks test score, but no significant difference was found between groups. The MusicGlove group did exhibit significantly greater improvements than the conventional exercise group in motor activity log quality of movement and amount of use scores 1 mo posttherapy (p = 0.007 and p = 0.04, respectively). Participants significantly increased their use of MusicGlove over time, completing 466 gripping movements per day on average at study end. MusicGlove therapy was not superior to conventional tabletop exercises for the primary end point but was nevertheless feasible and led to a significantly greater increase in self-reported functional use and quality of movement of the impaired hand than conventional home exercises.

    Clinical trial registration

    ClinicalTrials.gov; "Influence of Timing on Motor Learning"; NCT01769326; https://clinicaltrials.gov/ct2/show/NCT01769326.
      Cover page: Home-based hand rehabilitation after chronic stroke: Randomized, controlled single-blind trial comparing the MusicGlove with a conventional exercise programCreative Commons 'BY' version 4.0 license
      • Article
      • Peer Reviewed
      UC San Francisco Previously Published Works (2016)
      Despite the explosion in the numbers of cancer genomic studies, metastasis is still the major cause of cancer mortality. In breast cancer, approximately one-fifth of metastatic patients survive 5 years. Therefore, detecting the patients at a high risk of developing distant metastasis at first diagnosis is critical for effective treatment strategy. We hereby present a novel systems biology approach to identify driver mutations escalating the risk of metastasis based on both exome and RNA sequencing of our collected 78 normal-paired breast cancers. Unlike driver mutations occurring commonly in cancers as reported in the literature, the mutations detected here are relatively rare mutations occurring in less than half metastatic samples. By supposing that the driver mutations should affect the metastasis gene signatures, we develop a novel computational pipeline to identify the driver mutations that affect transcription factors regulating metastasis gene signatures. We identify driver mutations in ADPGK, NUP93, PCGF6, PKP2 and SLC22A5, which are verified to enhance cancer cell migration and prompt metastasis with in vitro experiments. The discovered somatic mutations may be helpful for identifying patients who are likely to develop distant metastasis.
        Cover page: Integrative analysis of mutational and transcriptional profiles reveals driver mutations of metastatic breast cancers
        • Article
        • Peer Reviewed
        UCLA Previously Published Works (2023)

        Background

        Stroke is the leading cause of mortality in China, with limited evidence of in-hospital burden obtained from nationwide surveys. We aimed to monitor and track the temporal trends and rural-urban disparities in cerebrovascular risk factors, management and outcomes from 2005 to 2015.

        Methods

        We used a two-stage random sampling survey to create a nationally representative sample of patients admitted for ischaemic stroke in 2005, 2010 and 2015. We sampled participating hospitals with an economic-geographical region-stratified random-sampling approach first and then obtained patients with a systematic sampling approach. We weighed our survey data to estimate the national-level results and assess changes from 2005 to 2015.

        Results

        We analysed 28 277 ischaemic stroke admissions from 189 participating hospitals. From 2005 to 2015, the estimated national hospital admission rate for ischaemic stroke per 100 000 people increased (from 75.9 to 402.7, Ptrend<0.001), and the prevalence of risk factors, including hypertension, diabetes, dyslipidaemia and current smoking, increased. The composite score of diagnostic tests for stroke aetiology assessment (from 0.22 to 0.36, Ptrend<0.001) and secondary prevention treatments (from 0.46 to 0.70, Ptrend<0.001) were improved. A temporal decrease was found in discharge against medical advice (DAMA) (from 15.2% (95% CI 13.7% to 16.7%) to 8.6% (8.1% to 9.0%); adjusted Ptrend=0.046), and decreases in in-hospital mortality (0.7% in 2015 vs 1.8% in 2005; adjusted OR (aOR) 0.52; 95% CI 0.32 to 0.85) and the composite outcome of in-hospital mortality or DAMA (8.4% in 2015 vs 13.9% in 2005; aOR 0.65; 95% CI 0.47 to 0.89) were observed. Disparities between rural and urban hospitals narrowed; however, disparities persisted in in-hospital management (brain MRI: rural-urban difference from -14.4% to -11.2%; cerebrovascular assessment: from -20.3% to -16.7%; clopidogrel: from -2.1% to -10.3%; anticoagulant for atrial fibrillation: from -10.9% to -8.2%) and in-hospital outcomes (DAMA: from 2.7% to 5.0%; composite outcome of in-hospital mortality or DAMA: from 2.4% to 4.6%).

        Conclusions

        From 2005 to 2015, improvements in hospital admission and in-hospital management for ischaemic stroke in China were found. A temporal improvement in DAMA and improvements in in-hospital mortality and the composite outcome of in-hospital mortality or DAMA were observed. Disparities between rural and urban hospitals generally narrowed but persisted.
          Cover page: Temporal trends and rural–urban disparities in cerebrovascular risk factors, in-hospital management and outcomes in ischaemic strokes in China from 2005 to 2015: a nationwide serial cross-sectional survey
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