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Does Naloxone Reinstate Secondary Hyperalgesia in Humans after Resolution of a Burn Injury? A Placebo-Controlled, Double-Blind, Randomized, Cross-Over Study

  • Author(s): Rowbotham, Michael
  • Pereira, MP
  • Werner, MU
  • Ringsted, TK
  • Rowbotham, MC
  • Taylor, BK
  • Dahl, JB
  • et al.

Published Web Location

http://europepmc.org/articles/PMC3669421?pdf=render
No data is associated with this publication.
Abstract

Introduction:Development of secondary hyperalgesia following a cutaneous injury is a centrally mediated, robust phenomenon. The pathophysiological role of endogenous opioid signalling to the development of hyperalgesia is unclear. Recent animal studies, ca

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