The sirtuins, oxidative stress and aging: An emerging link
- Author(s): Verdin, Eric
- Merksamer, PI
- Liu, Y
- He, W
- Hirschey, MD
- Chen, D
- et al.
Published Web Locationhttp://europepmc.org/articles/PMC3629286?pdf=render
Reactive oxygen species (ROS) are a family of compounds that can oxidatively damage cellular macromolecules and may influence lifespan. Sirtuins are a conserved family of nicotinamide adenine dinucleotide (NAD+)-dependent protein deacetylases that regulate
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