Skip to main content
eScholarship
Open Access Publications from the University of California

UC Irvine

UC Irvine Previously Published Works bannerUC Irvine

Skin model surface temperatures during single and multiple cryogen spurts used in laser dermatologic surgery.

  • Author(s): Ramirez-San-Juan, Julio C;
  • Aguilar, Guillermo;
  • Tuqan, Alia T;
  • Kelly, Kristen M;
  • Nelson, J Stuart
  • et al.

Published Web Location

https://doi.org/10.1002/lsm.20124Creative Commons 'BY' version 4.0 license
Abstract

Background

Although cryogen spray cooling (CSC) is used to minimize the risk of epidermal damage during laser dermatologic surgery, concern has been expressed that CSC may induce cryo-injury. In order to address this concern, it is necessary to evaluate the effects of prolonged exposure of human skin phantoms (HSP) to CSC.

Objective

To measure the minimum surface temperature (T(min)) and the time at which it occurs (t(Tmin)) as well as determine the time the sprayed HSP surface remains below 0 degrees C (sub-zero time, Deltat(s)) and -26 degrees C (residence time, Deltat(r)) during the application of single (SCS) and multiple (MCS) cryogen spurts. Two initial HSP substrate temperatures were studied, T(i): 23 and 70 degrees C.

Study design/materials and methods

An epoxy-based HSP was constructed to measure T(min), t(Tmin), Deltat(s), and Deltat(r), for 17 spray patterns: 1 SCS with a total cryo-delivery time (Deltat(c)) of 40 milliseconds; 8 MCS patterns with identical Deltat(c), but with a total cooling time (Deltat(total)) varying from 50 to 280 milliseconds; and 8 SCS patterns that matched the Deltat(total) of the MCS patterns.

Results

For both T(i), our results show that it is possible to distinguish between two different cooling regimes. For Deltat(total) ConclusionsThese results suggest that: (1) similar epidermal protection may be attained with SCS and MCS for Deltat(total)

Many UC-authored scholarly publications are freely available on this site because of the UC's open access policies. Let us know how this access is important for you.

Main Content
For improved accessibility of PDF content, download the file to your device.
Current View