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FLT3 D835 mutations confer differential resistance to type II FLT3 inhibitors
Published Web Location
http://europepmc.org/articles/PMC4675689?pdf=renderNo data is associated with this publication.
Abstract
© 2015 Macmillan Publishers Limited Activating mutations in FLT3 occur in ~30% of adult acute myeloid leukemia, primarily consisting of internal tandem duplication (ITD) mutations (~25%) and point mutations in the tyrosine kinase domain (~5%), commonly at
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