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A culture system to study oligodendrocyte myelination processes using engineered nanofibers
- Chan, Jonah;
- Mellon, Synthia;
- Lee, S;
- Leach, MK;
- Redmond, SA;
- Chong, SYC;
- Mellon, SH;
- Tuck, SJ;
- Feng, ZQ;
- Corey, JM;
- Chan, JR
Published Web Location
http://europepmc.org/articles/PMC3433633?pdf=renderNo data is associated with this publication.
Abstract
Current methods for studying central nervous system myelination necessitate permissive axonal substrates conducive to myelin wrapping by oligodendrocytes. We have developed a neuron-free culture system in which electron-spun nanofibers of varying sizes sub
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