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Oxytocin mediates early experience–dependent cross-modal plasticity in the sensory cortices
Published Web Location
https://doi.org/10.1038/nn.3634Abstract
This study shows that early neonatal sensory deprivation of one modality can impact cortical plasticity of other sensory cortices because of the reduction in dendritic release of oxytocin from paraventricular hypothalamic neurons. The study also shows that exogenous oxytocin can attenuate the effects of neonatal sensory deprivation on cortical plasticity, thus mimicking the beneficial effects of enriched sensory exposure.
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