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Rheology of Vitreous Gel

Abstract

The viscoelastic properties of the vitreous gel, major component in human eye, has not been investigated thoroughly so far. Despite our recent findings on the link between vitreous complications and several ocular diseases such as tractional retinal detachment, retinal tear, vitreous hemorrhage and glaucoma, there are still some unknown aspects that require more study to be done. Here, the emphasis is on characterization of the recent experimental tools invented at UCLA for analyzing rheology of the vitreous gel. We were able to present similar results in agreement with previous work. In addition to that, the relationship between the viscoelastic behavior patterns in a pair of eyes was investigated in different species. While the creep compliance behavior was different among species, we found a clear similarity pattern in creep compliance behavior within pairs in all species. This finding will significantly advance the future studies of biomechanics of vitreous gel such as more investigation on correlation between vitreous component interactions and vitreous related pathology or surgeries.

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