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Open Access Publications from the University of California

Signatures of mutational processes in human cancer.

  • Author(s): Van 'T Veer, Laura
  • Alexandrov, LB
  • Nik-Zainal, S
  • Wedge, DC
  • Aparicio, SAJR
  • Behjati, S
  • Biankin, AV
  • Bignell, GR
  • Bolli, N
  • Borg, A
  • Børresen-Dale, A-L
  • et al.

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All cancers are caused by somatic mutations; however, understanding of the biological processes generating these mutations is limited. The catalogue of somatic mutations from a cancer genome bears the signatures of the mutational processes that have been o

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