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Microbiota-liberated host sugars facilitate post-antibiotic expansion of enteric pathogens
- Ng, Katharine M;
- Ferreyra, Jessica A;
- Higginbottom, Steven K;
- Lynch, Jonathan B;
- Kashyap, Purna C;
- Gopinath, Smita;
- Naidu, Natasha;
- Choudhury, Biswa;
- Weimer, Bart C;
- Monack, Denise M;
- Sonnenburg, Justin L
Published Web Location
https://doi.org/10.1038/nature12503Abstract
Antibiotic treatment disturbs the commensal microbiota and is often followed by infection with enteric pathogens such as Salmonella typhimurium and Clostridium difficile; pathogen expansion is fuelled by antibiotic-driven accumulation of commensal-liberated host mucosal carbohydrates.
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