Skip to main content
The M5nr: a novel non-redundant database containing protein sequences and annotations from multiple sources and associated tools.
- Author(s): Wilke, Andreas;
- Harrison, Travis;
- Wilkening, Jared;
- Field, Dawn;
- Glass, Elizabeth M;
- Kyrpides, Nikos;
- Mavrommatis, Konstantinos;
- Meyer, Folker
- et al.
Published Web Locationhttps://doi.org/10.1186/1471-2105-13-141
BackgroundComputing of sequence similarity results is becoming a limiting factor in metagenome analysis. Sequence similarity search results encoded in an open, exchangeable format have the potential to limit the needs for computational reanalysis of these data sets. A prerequisite for sharing of similarity results is a common reference.
DescriptionWe introduce a mechanism for automatically maintaining a comprehensive, non-redundant protein database and for creating a quarterly release of this resource. In addition, we present tools for translating similarity searches into many annotation namespaces, e.g. KEGG or NCBI's GenBank.
ConclusionsThe data and tools we present allow the creation of multiple result sets using a single computation, permitting computational results to be shared between groups for large sequence data sets.
For improved accessibility of PDF content, download the file to your device.