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Molecular basis for 5-carboxycytosine recognition by RNA polymerase II elongation complex

et al.

Published Web Location

https://doi.org/10.1038/nature14482
Abstract

Structural and biochemical studies of RNA polymerase II (Pol II) assembled on DNA containing 5-carboxycytosine reveals that Pol II can sense the oxidized methylation state of DNA and transiently slows down during transcription.

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