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Detection of identity by descent using next-generation whole genome sequencing data

  • Author(s): Baranzini, Sergio
  • Su, SY
  • Kasberger, J
  • Byerley, W
  • Liao, W
  • Oksenberg, J
  • Sherr, E
  • Jorgenson, E
  • et al.

Published Web Location

http://europepmc.org/articles/PMC3403908?pdf=render
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Abstract

Background: Identity by descent (IBD) has played a fundamental role in the discovery of genetic loci underlying human diseases. Both pedigree-based and population-based linkage analyses rely on estimating recent IBD, and evidence of ancient IBD can be used

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