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Altitude adaptation in Tibetans caused by introgression of Denisovan-like DNA

et al.

Published Web Location

https://doi.org/10.1038/nature13408
Creative Commons 'BY-NC-ND' version 4.0 license
Abstract

Admixture with other hominin species helped humans to adapt to high-altitude environments; the EPAS1 gene in Tibetan individuals has an unusual haplotype structure that probably resulted from introgression of DNA from Denisovan or Denisovan-related individuals into humans, and this haplotype is only found in Denisovans and Tibetans, and at low frequency among Han Chinese.

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