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αTAT1 catalyses microtubule acetylation at clathrin-coated pits
- Montagnac, Guillaume;
- Meas-Yedid, Vannary;
- Irondelle, Marie;
- Castro-Castro, Antonio;
- Franco, Michel;
- Shida, Toshinobu;
- Nachury, Maxence V;
- Benmerah, Alexandre;
- Olivo-Marin, Jean-Christophe;
- Chavrier, Philippe
Published Web Location
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970258/No data is associated with this publication.
Abstract
In eukaryotic cells, a subset of microtubules undergoes acetylation, resulting in stabilization: here, clathrin-coated pits are shown to control microtubule acetylation through a direct interaction between the α-tubulin acetyltransferase αTAT1 and the clathrin adaptor AP2, promoting directional cell migration.
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