Intraoperative hypernatremia and polyuric syndrome induced by dexmedetomidine.
- Author(s): Ji, Fuhai
- Liu, Hong
- et al.
Published Web Locationhttps://doi.org/10.1007/s00540-013-1562-3
Hypernatremia and polyuria are the main symptoms of diabetes insipidus. Polyuria is characterized by a 24-h urine volume in excess of 40-50 ml/kg in adults. Dexmedetomidine, a highly selective, short-acting intravenous alpha-2 agonist, is used as a component of anesthesia, and has been suspected to induce polyuric syndrome. We report a patient who presented with severe hypernatremia and polyuria after intravenous infusion of dexmedetomidine.