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Effects of Caenorhabditis elegans sgk-1 mutations on lifespan, stress resistance, and DAF-16/FoxO regulation

  • Author(s): Ashrafi, Kaveh
  • Chen, ATY
  • Guo, C
  • Dumas, KJ
  • Hu, PJ
  • et al.

Published Web Location

http://europepmc.org/articles/PMC3824081?pdf=render
No data is associated with this publication.
Abstract

The AGC family serine-threonine kinases Akt and Sgk are similar in primary amino acid sequence and in vitro substrate specificity, and both kinases are thought to directly phosphorylate and inhibit FoxO transcription factors. In the nematode Caenorhabditis

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