- Main
Studies in the Methods and Applications of Comparative Effectiveness Research: Hospice Stay Determinants, Human Papillomavirus Vaccination in Men, and Analytic Techniques for Evaluating Experimental and Non-experimental Data
- Sunkara, Srinivasu
- Advisor(s): Kaplan, Robert M
Abstract
This dissertation applies techniques in comparative effectiveness research (CER) to understand the determinants of hospice stay duration, the cost-effectiveness of Human Papillomavirus (HPV) vaccination, and the optimal method for evaluating non-experimental and experimental data. The research on hospice stay duration uses data from the Dartmouth Atlas. It finds that for the logarithm of hospice days, nurse staffing numbers are a significant determinant of length-of-stay. Total Medicare reimbursements go down by $117 for each day that a patient stays in hospice. The HPV paper aggregates results across 7 published papers. It finds that male-female HPV vaccination is cost-effective at a $100,000/QALY cost-effectiveness threshold. Finally, the statistics paper compares the accuracy of linear regression, propensity score matching, and simple subtraction for approximating the results of a RCT. It finds all methods excepting simple subtraction and nearest neighbor propensity score matching produce results that are not significantly different from the RCT result.
Main Content
Enter the password to open this PDF file:
-
-
-
-
-
-
-
-
-
-
-
-
-
-