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Adjunctive Corticosteroid Therapy in the Treatment of Coccidioidal Meningitis

  • Author(s): Thompson, GR
  • Blair, JE
  • Wang, S
  • Bercovitch, R
  • Bolaris, M
  • Van Den Akker, D
  • Lopez, R
  • Heidari, A
  • Catanzaro, A
  • Cadena, J
  • Chin-Hong, P
  • Spellberg, B
  • Johnson, R
  • et al.
Abstract

© The Author 2017. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. Coccidioidal meningitis (CM) has high morbidity, and adjunctive measures to improve outcomes are needed. Using an established multicenter retrospective cohort study of CM (N = 221), we found that patients receiving adjunctive corticosteroids had a significant reduction in secondary cerebrovascular events (P =.0049). Those with CM-associated cerebrovascular events (8%) may benefit from short-term corticosteroids.

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