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Adjunctive Corticosteroid Therapy in the Treatment of Coccidioidal Meningitis
- Thompson, George R;
- Blair, Janis E;
- Wang, Sharon;
- Bercovitch, Robert;
- Bolaris, Michael;
- Van Den Akker, Dane;
- Lopez, Rodrigo;
- Heidari, Arash;
- Catanzaro, Antonino;
- Cadena, Jose;
- Chin-Hong, Peter;
- Spellberg, Brad;
- Johnson, Royce
Published Web Location
https://doi.org/10.1093/cid/cix318Abstract
Coccidioidal meningitis (CM) has high morbidity, and adjunctive measures to improve outcomes are needed. Using an established multicenter retrospective cohort study of CM (N = 221), we found that patients receiving adjunctive corticosteroids had a significant reduction in secondary cerebrovascular events (P = .0049). Those with CM-associated cerebrovascular events (8%) may benefit from short-term corticosteroids.
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