Skip to main content
eScholarship
Open Access Publications from the University of California

Psychosocial interventions and medication adherence in bipolar disorder

  • Author(s): Depp, CA
  • Moore, DJ
  • Patterson, TL
  • Lebowitz, BD
  • Jeste, DV
  • et al.

Published Web Location

https://www.ncbi.nlm.nih.gov/pubmed/18689293
No data is associated with this publication.
Abstract

Recent research has indicated that psychosocial interventions can have a valuable role in reducing the substantial psychosocial disability associated with bipolar disorder. Randomized controlled trials of these interventions indicate that improvements are seen in symptoms, psychosocial functioning, and treatment adherence. These interventions, systematically presented in the form of standardized treatment manuals, vary in format, duration, and theoretical basis. All are meant to augment pharmacotherapy, which represents the standard of treatment in the field. Modalities that have gathered the most empirical support include cognitive-behavioral therapy, family-focused therapy, interpersonal and social rhythms therapy, and psychoeducation. The enhancement of adherence to pharmacotherapy is a common therapeutic target, due to the association of nonadherence with higher relapse rates, hospitalization, and health care costs among people with bipolar disorder. Given the complexity of nonadherence behavior, multicomponent interventions are often required. In this review, we provide an overview of the rationale, evidence base, and major psychotherapeutic approaches in bipolar disorder, focusing on the assessment and enhancement of medication adherence. © 2008, LLS SAS.

Many UC-authored scholarly publications are freely available on this site because of the UC Academic Senate's Open Access Policy. Let us know how this access is important for you.

Main Content

This item is under embargo until October 3, 2019.

You may have access to the publisher's version here:

https://www.ncbi.nlm.nih.gov/pubmed/18689293Notify me by email when this item becomes available