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MHC class II-dependent B cell APC function is required for induction of CNS autoimmunity independent of myelin-specific antibodies

  • Author(s): Zamvil, Scott
  • Molnarfi, N
  • Schulze-Topphoff, U
  • Weber, MS
  • Patarroyo, JC
  • Prod'homme, T
  • Varrin-Doyer, M
  • Shetty, A
  • Linington, C
  • Slavin, AJ
  • Hidalgo, J
  • et al.

Published Web Location

http://europepmc.org/articles/PMC3865476?pdf=render
No data is associated with this publication.
Abstract

Whether B cells serve as antigen-presenting cells (APCs) for activation of pathogenic T cells in the multiple sclerosis model experimental autoimmune encephalomyelitis (EAE) is unclear. To evaluate their role as APCs, we engineered mice selectively deficie

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